Head and Neck Cancer Incidence Trends in Young Americans, 1973-1997, With a Special Analysis for Tongue Cancer

摘要: Objective: To examine the temporal changes in head and neck cancer young adults United States. Methods: Using surveillance database from National Cancer Institute Surveillance, Epidemiology, End Results (SEER) Program, we calculated age-adjusted incidence rates for cancers. joinpoint regression model, described tongue trends established statistical significance of changes. We also compared 5-year survival cancer. Results: From 1973 to 1997, there were 63409 patients with 9 SEER registries. Of these, 3339 younger than 40 years. The remained stable groups older years comparing 1973-1984 1985-1997 data. In contrast, increased approximately 60% during same period. detected a significant increase until 1985, estimated annual percentage change being 6.7% (95% confidence interval, 2.7%-10.8%; P<.001). After stopped rising but steadily high. was related birth cohorts between 1938 1948, absolute ranged 11.7% (<40 old) 6.6% (40-64 1985-1997, most improvement occurring Americans regional or distant disease (27% 21%, respectively). Conclusions: A sharp increasing trend may be attributed persons born after 1938. reason is uncertain. Improved suggest emergence distinct process that apparent white not black populations.