Left ventricular hypertrophy in renal failure

摘要: Left ventricular hypertrophy in renal failure. In patients with terminal failure, left (LVH) is extremely common. It found approximately 60 to 80% of starting replacement therapy. The main causes LVH are increased preload from hypervolemia and afterload peripheral resistance, giving rise a mixture excentric concentric hypertrophy, but other factors (high cardiac output anemia arteriovenous (A-V) fistula, altered compliance central arteries, activation local systems such as renin endothelin) also play role. clinical importance derives the fact that predictor death dialyzed independent blood pressure. accompanied by microvascular disease marked interstitial fibrosis (more than seen non-renal similar degrees hypertension). Recent findings suggest LV remodeling starts early even normotensive glomerulonephritis when GFR still normal. strategies reduce include reduction hypervolemia, (near) normalization hemoglobin lowering pressure, particularly administration angiotensin converting enzyme inhibitors.