Diagnosing and treating active myocarditis.

摘要: Abstract The treatment of dilated cardiomyopathy is palliative and, hence, has little effect on the natural history. Therapy directed toward cause rather than will be necessary before mortality can affected. Active myocarditis postulated to in a subset patients. A model murine coxsackievirus B3 immunopathogenic parallels disease humans and suggests that persistent autoimmune reactivity following viral clearance leads progressive myocyte damage cardiomyopathy. In preliminary uncontrolled studies, patients with have shown clinical histologic improvement addition immunosuppressive therapy, but there may also significant rate spontaneous improvement. multicenter study currently acquiring designed determine efficacy immunosuppression history active myocarditis.