Methods of using black bear parathyroid hormone
作者： Seth W. Donahue
DOI:
关键词: BAX Protein 、 Cell 、 Antibody 、 Parathyroid hormone 、 Bone mineral 、 Endocrinology 、 Chemistry 、 Internal medicine 、 Apoptosis 、 Bone mass 、 Transcriptional regulation
摘要: Black bear parathyroid hormone (PTH) and functional fragments thereof are provided. Also provided methods of using black PTH for increasing cAMP in a bone-forming cell; reducing apoptosis decreasing the ratio expression levels Bax protein to Bcl-2 level one or more bone matrix protein, transcriptional activator, regulator enhancing mineral density, mass, loss, incidence fractures, any combination thereof, subject; also antibodies directed against thereof.
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