Antioxidant defenses in the ocular surface.

作者: Ying Chen , Gaurav Mehta , Vasilis Vasiliou

DOI: 10.1016/S1542-0124(12)70185-4

关键词: Oxygen tensionVitamin EAnatomyBiologyMetabolic enzymesAntioxidantOxidative stressOcular surfaceCell biologyReactive oxygen speciesCornea

摘要: The human eye is subjected constantly to oxidative stress due to daily exposure to sunlight, high metabolic activities, and oxygen tension. Reactive oxygen species generated from …

参考文章(118)
Thomas D. Tenkate, Ultraviolet Radiation: Human Exposure and Health Risks. Journal of Environmental Health. ,vol. 61, pp. 9- 15 ,(1998)
Usha P. Andley, Leo T. Chylack, Timothy P. Fleming, Johng S. Rhim, Propagation and Immortalization of Human Lens Epithelial Cells in Culture Investigative Ophthalmology & Visual Science. ,vol. 35, pp. 3094- 3102 ,(1994)
A Ringvold, E Anderssen, I Kjønniksen, Ascorbate in the corneal epithelium of diurnal and nocturnal species. Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 2774- 2777 ,(1998)
Amund Ringvold, Erlend Anderssen, Inge Kjønniksen, Distribution of Ascorbate in the Anterior Bovine Eye Investigative Ophthalmology & Visual Science. ,vol. 41, pp. 20- 23 ,(2000)
Roswell R. Pfister, Christopher A. Paterson, Sonia Anderson Hayes, Effects of topical 10% ascorbate solution on established corneal ulcers after severe alkali burns. Investigative Ophthalmology & Visual Science. ,vol. 22, pp. 382- 385 ,(1982)
Bhargavan Chakrapani, Frank J. Giblin, Venkat N. Reddy, Li-Ren Lin, The Effect of Aqueous Humor Ascorbate on ultraviolet-B-induced DNA Damage in Lens Epithelium Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 344- 350 ,(1998)
A. Wegener, M. Heinitz, M. Dwinger, Experimental evidence for interactive effects of chronic UV irradiation and nutritional deficiencies in the lens. Developments in ophthalmology. ,vol. 35, pp. 113- 124 ,(2002) , 10.1159/000060815
David C. Musch, Frank J. Giblin, Daniel L. Boyle, Elke Lütjen-Drecoll, Venkat N. Reddy, Nalin J. Unakar, Loan Dang, Larry J. Takemoto, Tina Knoernschild, Anselm Juenemann, Li-Ren Lin, Ye-Shih Ho, Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice. Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 3247- 3255 ,(2001)
Alton Meister, [1] Glutathione metabolism Methods in Enzymology. ,vol. 251, pp. 3- 7 ,(1995) , 10.1016/0076-6879(95)51106-7
Thomas Brännström, Stefan L. Marklund, Marie-Louise Sentman, Kurt Karlsson, Anders Behndig, Corneal endothelial integrity in mice lacking extracellular superoxide dismutase. Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 2784- 2788 ,(2001)