Temperature gradient interaction chromatography of polymers

摘要: Abstract Size exclusion chromatography (SEC) is the most widely employed chromatographic separation technique for characterization of synthetic polymers. SEC separates polymer molecules according to their chain size utilizing size-dependent pore accessibility molecules. Since depends on not only molecular weight (MW) but also other characteristics such as composition, architecture, and microstructure, cannot separate, instance, nonlinear homopolymers MW or copolymers composition. In contrast SEC, interaction (IC) fractionates polymers strength between sorbent. As a result, IC sensitive chemical nature unlike size-sensitive SEC. Furthermore, one can access critical condition by adjusting solute with sorbent until contributions retention are exactly compensated. At condition, different coelute. Therefore liquid (LC) at (LCCC) unique tool LC since peak dispersion due distribution be suppressed effective analyses characteristics. Recently, separations using two-dimensional various combinations IC, LCCC increasingly used multivariate distributions. For separations, needs controlled judiciously during elution. this purpose, either solvent gradient temperature elution often used. chapter, principles applications methods reviewed an emphasis method.