Fatty Acid Synthetases of Eukaryotic Cells

作者: Salih J. Wakil , James K. Stoops

DOI: 10.1007/978-1-4613-2355-6_2

关键词: Acyl carrier proteinBiotinPyruvate carboxylaseChemistryFatty acid synthesisCatalysisFatty Acid SynthetasesUropygial glandBiochemistryLiving cell

摘要: The synthesis of long-chain fatty acids, such as palmitic, occurs in the living cell by head-to-tail condensation C2 units acetyl-CoA. two steps. First, acetyl-CoA is converted to malonyl-CoA carboxylase, a multienzyme system containing biotin [Eq. (1); for recent review see Wakil et al., 1983]. second step (Eq. 2) conversion and palmitate, catalyzed acid synthetases (FAS) presence NADPH.

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