Surgery in the Treatment of Malignant Glioma: Current Status and Future Perspectives

摘要: Brain gliomas have been surgically removed for over 100 years. In the early days mortality was 20%, but it obvious even then that extensive resection produces better results than does minimal resection, with a of 10%. The reduced dramatically, to below 3%, introduction dexamethasone in 1960s (Jelsma and Bucy 1967). Patients were also seen be neurological condition immediate postoperative period after an partial they had longer mean survival. More recent studies shown surgery alone prolongs survival by about 14 weeks (Shapiro 1982; Walker et al. 1978). Postoperative morbidity is under 20% not affected extent surgical (Fadul 1988). On contrary, patients complete suffer fewer complications such as hemorrhage or herniation those biopsy only. However, total tumor situated midline parietal lobes may leave patient severe deficits.