Self-Activated Fluorescent Hydroxyapatite Nanoparticles: A Promising Agent for Bioimaging and Biolabeling
作者： Ketaki Deshmukh , M. Monsoor Shaik , Sutapa Roy Ramanan , Meenal Kowshik
DOI: 10.1021/ACSBIOMATERIALS.6B00169
关键词: Nanotechnology 、 Detection limit 、 Fluorescence 、 Amine gas treating 、 Dimethyl sulfoxide 、 Fluorescence-lifetime imaging microscopy 、 Combinatorial chemistry 、 Materials science 、 Nanomaterials 、 Spectroscopy 、 Molecular electronic transition
摘要: Bioimaging has drastically transformed the field of medicine, and made process diagnosis easy fast. Visualization complete organ to complex biological processes now become possible. Among various imaging processes, fluorescence using nontoxic fluorescent nanomaterials is advantageous for several beneficial features including high sensitivity, minimal invasiveness, safe detection limit. In this study, we have synthesized characterized a new class nontoxic, self-activated hydroxyapatite nanoparticles (fHAps) with different aspect ratios (thin-rods, short-rods, rods) by changing stabilizing agents (triethyl amine acetyl acetone) solvents (water dimethyl sulfoxide). fHAps showed excellent broad emission spectrum ranging from 350 750 nm maximum at 502 nm. The presence was attributed electronic transition in asymmetric structure as confirmed ESR spectroscopy absence f...
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