作者: J. A. Pariente , J. A. Madrid , G. M. Salido
DOI: 10.1007/BF02022981
关键词: Cimetidine 、 Biology 、 Pancreatic Exocrine Secretion 、 Internal medicine 、 Pancreas 、 Dimaprit 、 Histamine 、 Agonist 、 Histamine H2 receptor 、 Histamine receptor 、 Endocrinology 、 Toxicology 、 Immunology 、 Pharmacology (medical) 、 Pharmacology
摘要: Histamine H2-receptor antagonists cimetidine and oxmetidine, agonist dimaprit, H1-receptor antagonist chlorpheniramine 2-thiazolylethylamine were tested for their effects on unstimulated pancreatic exocrine secretion in anaesthetized rabbits fitted with an acute cannula. Intravenous administration of H1 induces a dose-dependent increase but have the opposite effects. H2 similar ones produced after infusion. The implications receptors are discussed.