Mediastinal growing teratoma syndrome

摘要: Background. The growing teratoma syndrome refers to the phenomenon whereby germ cell tumors enlarge after chemotherapy despite complete eradication of malignant cells and normalization serum tumor markers. This clinical scenario must be differentiated from that in which maintain their characteristics with elevated levels Methods. Hospital record review was conducted 2 cases. Results. Two male patients are presented, 1 a metastatic both retroperitoneum mediastinum (with α-fetoprotein level) primary β-human chorionic gonadotropin levels). After completion markers, presented pulmonary symptoms attributable massively enlarging mediastinal teratomas. roentgenographic features thoracic manifestations syndrome, as well its management, reviewed. Conclusions. or whose markers normalize, mass may represent syndrome.