Induction of neoantigen-reactive T cells from healthy donors

作者: Muhammad Ali , Zsofia Foldvari , Eirini Giannakopoulou , Maxi-Lu Böschen , Erlend Strønen

DOI: 10.1038/S41596-019-0170-6

关键词: BiologyTransfectionCancer researchT-cell receptorAntigenT cellReceptorIn silicoCD8Epitope

摘要: The identification of immunogenic neoantigens and their cognate T cells represents the most crucial and rate-limiting steps in the development of personalized cancer immunotherapies …

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