Erythropoietin and iron.

作者: Gere Sunder-Plassmann , Walter H. Hörl

DOI:

关键词: ErythropoietinTransferrinFerritinKidney diseasePeritoneal dialysisInternal medicineHemodialysisIron-deficiency anemiaGastroenterologyMedicineEndocrinologyIron deficiency

摘要: Careful evaluation of iron status is pivotal importance in end-stage renal disease patients before and during r-HuEPO therapy. Absolute (ferritin 5%) deficiency are the main reasons for hyporesponsiveness. Adequate supplementation allows significant reduction dosage costs. Oral recommended predialysis peritoneal dialysis with serum ferritin > 100 micrograms/l, whereas i.v. therapy choice hemodialysis patients. However, neutrophil impairment other possible side-effects (e.g. cardiovascular complications, malignancy) as a result suggest that overtreatment should be avoided.

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