Strategies of polymeric nanoparticles for enhanced internalization in cancer therapy.

作者: Lu Sun , Qinjie Wu , Feng Peng , Lei Liu , Changyang Gong

DOI: 10.1016/J.COLSURFB.2015.07.013

关键词: PEG ratioInternalizationEthylene glycolDextranPharmacologyCancer cellEthylene oxideChemistryAcrylic acidBiophysicsNanoparticle

摘要: … The RGDfK targeted conjugate showed active binding to αvβ3 integrins in both human … To further retain NPs within tumor tissue and to enhance cellular uptake, cell-penetrating peptides …

参考文章(221)
Li Tang, Rong Tong, Virginia J. Coyle, Qian Yin, Holly Pondenis, Luke B. Borst, Jianjun Cheng, Timothy M. Fan, Targeting tumor vasculature with aptamer-functionalized doxorubicin-polylactide nanoconjugates for enhanced cancer therapy. ACS Nano. ,vol. 9, pp. 5072- 5081 ,(2015) , 10.1021/ACSNANO.5B00166
Beatrice Uziely, Yechezkel Barenholz, Raphael Catane, Tamar Safra, Alberto Gabizon, Francis Martin, Rivka Cohen, Anthony Huang, Bela Kaufman, Prolonged Circulation Time and Enhanced Accumulation in Malignant Exudates of Doxorubicin Encapsulated in Polyethylene-glycol Coated Liposomes Cancer Research. ,vol. 54, pp. 987- 992 ,(1994)
P.B.A.A. van Driel, J.R. van der Vorst, F.P.R. Verbeek, S. Oliveira, T.J.A. Snoeks, S. Keereweer, B. Chan, M.C. Boonstra, J.V. Frangioni, P.M.P. van Bergen en Henegouwen, A.L. Vahrmeijer, C.W.G.M. Lowik, Intraoperative fluorescence delineation of head and neck cancer with a fluorescent anti-epidermal growth factor receptor nanobody. International Journal of Cancer. ,vol. 134, pp. 2663- 2673 ,(2014) , 10.1002/IJC.28601
Radoslav Savic, Laibin Luo, Adi Eisenberg, Dusica Maysinger, Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles Science. ,vol. 300, pp. 615- 618 ,(2003) , 10.1126/SCIENCE.1078192
Evangelos S. Gragoudas, Anthony P. Adamis, Emmett T. Cunningham, Matthew Feinsod, David R. Guyer, Pegaptanib for Neovascular Age-Related Macular Degeneration The New England Journal of Medicine. ,vol. 351, pp. 2805- 2816 ,(2004) , 10.1056/NEJMOA042760
Joan Domingo-Espín, Valérie Petegnief, Núria de Vera, Oscar Conchillo-Solé, Paolo Saccardo, Ugutz Unzueta, Esther Vazquez, Juan Cedano, Luciana Negro, Xavier Daura, Hugo Peluffo, Anna M. Planas, Antonio Villaverde, Neus Ferrer-Miralles, RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factors Nanomedicine: Nanotechnology, Biology and Medicine. ,vol. 8, pp. 1263- 1266 ,(2012) , 10.1016/J.NANO.2012.06.005
Pedro M. Valencia, Mikhail H. Hanewich-Hollatz, Weiwei Gao, Fawziya Karim, Robert Langer, Rohit Karnik, Omid C. Farokhzad, Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles. Biomaterials. ,vol. 32, pp. 6226- 6233 ,(2011) , 10.1016/J.BIOMATERIALS.2011.04.078
Domenica Musumeci, Daniela Montesarchio, Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer. Pharmacology & Therapeutics. ,vol. 136, pp. 202- 215 ,(2012) , 10.1016/J.PHARMTHERA.2012.07.011
Chloe Kim, Justin F. Galloway, Kwan Hyi Lee, Peter C. Searson, Universal antibody conjugation to nanoparticles using the Fcγ receptor I (FcγRI): quantitative profiling of membrane biomarkers Bioconjugate Chemistry. ,vol. 25, pp. 1893- 1901 ,(2014) , 10.1021/BC5003778