Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice
作者： Lara S. Hwa , Anna J. Nathanson , Akiko Shimamoto , Jillian K. Tayeh , Allison R. Wilens
DOI: 10.1007/S00213-015-3925-Y
关键词: Glutamatergic 、 Glutamate receptor 、 Psychology 、 NMDA receptor 、 Memantine 、 Kindling 、 Poison control 、 Ethanol 、 Aggression 、 Internal medicine 、 Endocrinology 、 Anesthesia
摘要: Rationale Disrupted social behavior, including occasional aggressive outbursts, is characteristic of withdrawal from long-term alcohol (EtOH) use. Heavy EtOH use and exaggerated responses during may be treated using glutamatergic N-methyl-D-aspartate receptor (NMDAR) antagonists.
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