The Development of Cancer Vaccines for the Treatment of Metastatic Melanoma
作者： F. M. Marincola , S. A. Ronseberg
DOI: 10.1007/978-2-8178-0918-2_11
关键词: Biology 、 Virology 、 Immune system 、 Cancer vaccine 、 Cell 、 Major histocompatibility complex 、 Immunization 、 T cell 、 Antibody 、 Pathogen
摘要: Immunization against pathogens induces humoral as well cellular immune responses. While the former is directed toward extra-cellular invaders, latter proteins produced by following their infection of permissive cells. Like other intracellular proteins, viral products are enzymatically degraded into short peptides (9–11 amino acids in length) and presented on surface infected cells association with Major Histocompatibility Complex (MHC) class I molecules: a requirement for T cell recognition. Vaccines aimed at prevention disease might be particularly effective because they can arm host powerful neutralizing antibodies subsequent infections which results dramatic reduction load pathogen reaching target cell. After hidden host’s cells, system relies predominantly function. Clearing will this point depend balance between efficiency response protective strategies adopted [1].
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sci-hub.st 参考文章(79)
E. Appella, J. R. Yannelli, M. El-Gamil, Y. Kawakami, S. A. Rosenberg, P. F. Robbins, K. Sakaguchi, Rongfu Wang, Xiaoqiang Kang, Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes. Journal of Immunology. ,vol. 155, pp. 1343- 1348 ,(1995)
F. M. Burnet, The concept of immunological surveillance. Progress in Experimental Tumor Research. ,vol. 13, pp. 1- 27 ,(1970) , 10.1159/000386035
Francesco M. Marincola, Janice Nicole Cormier, Steven A. Rosenberg, Michael L. Salgaller, Michael L. Salgaller, Immunization against Epitopes in the Human Melanoma Antigen gp100 following Patient Immunization with Synthetic Peptides Cancer Research. ,vol. 56, pp. 4749- 4757 ,(1996)
H M Grey, G Hermanson, M F del Guercio, R T Kubo, C Perez, J Sidney, A Sette, Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype. Journal of Immunology. ,vol. 154, pp. 685- 693 ,(1995)
M. J. W. Visseren, M. E. Ressing, E. I. H. Van Der Voort, C. J. M. Melief, W. M. Kast, A. Van Elsas, P. I. Schrier, CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells. Journal of Immunology. ,vol. 154, pp. 3991- 3998 ,(1995)
Maria P. Bettinotti, Francesco M. Marincola, Janice N. Cormier, Monica Panelli, Kenneth K. Parker, Kang Hun Lee, Christina J. Kim, Matthew Roden, Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy. Journal of Immunology. ,vol. 161, pp. 877- 889 ,(1998)
Charles M. Balch, Arabella B. Tilden, Kyogo Itoh, Interleukin 2 Activation of Cytotoxic T-Lymphocytes Infiltrating into Human Metastatic Melanomas Cancer Research. ,vol. 46, pp. 3011- 3017 ,(1986)
V Barnaba, G Cappelli, M Paroli, M S Bonavita, G De Petrillo, V L Burgio, A Franco, I Santilio, R Benvenuto, C Balsano, Selective expansion of cytotoxic T lymphocytes with a CD4+CD56+ surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with Hepatitis B virus. Journal of Immunology. ,vol. 152, pp. 3074- 3087 ,(1994)
William E. Biddison, Ettore Appella, Flavio Arienti, Giorgio Parmiani, Francesco M. Marincola, Licia Rivoltini, Kathleen Barracchini, Arabella Mazzocchi, Douglas J. Loftus, Michael L. Salgaller, Binding and presentation of peptides derived from melanoma antigens MART-1 and glycoprotein-100 by HLA-A2 subtypes. Implications for peptide-based immunotherapy. Journal of Immunology. ,vol. 156, pp. 3882- 3891 ,(1996)
R C Hendrickson, D F Hunt, C L Slingluff, J C Skipper, S N Wagner, V H Engelhard, D D Deacon, D J Kittlesen, N L Harthun, Shared epitopes for HLA-A3-restricted melanoma-reactive human CTL include a naturally processed epitope from Pmel-17/gp100. Journal of Immunology. ,vol. 157, pp. 5027- 5033 ,(1996)