Simple Fluorescent Pyrimidine Analogues Detect the Presence of DNA Abasic Sites
作者： Nicholas J. Greco , Yitzhak Tor
DOI: 10.1021/JA052000A
关键词: Duplex (building) 、 Fluorescence 、 Fluorescence spectrometry 、 Stereochemistry 、 Chemistry 、 Nucleic acid 、 Pyrimidine analogue 、 Denaturation (biochemistry) 、 DNA 、 A-DNA 、 Biochemistry 、 Colloid and Surface Chemistry 、 General chemistry 、 Catalysis
摘要: A family of simple pyrimidine analogues has been synthesized, and their photophysical properties have investigated. The most responsive the was incorporated in DNA. This isosteric fluorescent DNA analogue monitors denaturation a duplex via fluorescence positively detects presence abasic sites duplexes.
acs.org
sci-hub.se 参考文章(0)