HOST-PARASITE RELATIONSHIPS AMONG GROUP A STREPTOCOCCI I.

摘要: Willoughby, Donald S. (University of Minnesota, Minneapolis), Yael Ginzburg, and Dennis W. Watson. Host-parasite relationships among group A streptococci. I. Hyaluronic acid production by virulent avirulent strains. J. Bacteriol. 87: 1452–1456. 1964.—Intradermal passage streptococcal strains in rabbits is an easy effective technique for selecting organisms capable producing increased amounts hyaluronic acid. Glutamine was required vitro hyaluronate production, although the requirement varied with organism tested. The type 18 cells produced maximal presence 0.01% glutamine compared 0.1% more 28; after animal passage, 28 decreased to 0.01%. Organisms selected small quantities absence exogenous source glutamine. Glucose at a concentration 1% gave greatest stimulation formation. Growth studies indicated similar rates multiplication types yet, rate under these conditions much greater 18. Because observations, it suggested that contributing factor virulence