Acupuncture for Chemotherapy-Induced Neutropenia in Patients with Gynecologic Malignancies: A Pilot Randomized, Sham-Controlled Clinical Trial

作者: Weidong Lu , Ursula A. Matulonis , Anne Doherty-Gilman , Hang Lee , Elizabeth Dean-Clower

DOI: 10.1089/ACM.2008.0589

关键词: Clinical trialSurgeryAbsolute neutrophil countRandomized controlled trialMedicineMyelosuppressive ChemotherapyAcupunctureInternal medicineCancerNeutropeniaChemotherapy

摘要: Abstract Objectives: The objective of this study was to investigate the effect acupuncture administered during myelosuppressive chemotherapy on white blood cell (WBC) count and absolute neutrophil (ANC) in patients with ovarian cancer. Design: This is a pilot, randomized, sham-controlled clinical trial. Patients received active versus sham while undergoing chemotherapy. A standardized protocol employed manual electrostimulation. frequency treatment 2–3 times per week for total 10 sessions, starting 1 before second cycle Setting: setting two outpatient academic centers Subjects: Twenty-one (21) newly diagnosed recurrent cancer were subjects. Outcome measures: WBC count, ANC, plasma granulocyte colony-stimulating factor (G-CSF ) assessed weekly. Results: median leukocyte value arm at first day third cyc...

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