Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide.
作者： Jila Sadighi , Saharnaz Nedjat , Rahele Rostami
DOI: 10.1017/S1368980019002179
关键词: Public health 、 Serum ferritin level 、 Iron status 、 Iron deficiency 、 Meta-analysis 、 Sri lanka 、 Ferritin 、 Toxicology 、 Flour fortification 、 Medicine
摘要: Objective Assess the effectiveness of iron-fortified flour on iron status. Design Systematic review and meta-analysis. Setting Argentina, Australia, Azerbaijan, Bangladesh, Brazil, Cameroon, Chile, China, Costa Rica, Cote d'Ivoire, Denmark, India, Iran, Jordan, Kazakhstan, Kenya, Kuwait, Mongolia, Morocco, Norway, South Africa, Sri Lanka, Tajikistan, Thailand, UK, USA, Uzbekistan, Venezuela, Vietnam, Zambia. Participants Fifty-two articles (ninety-four trials) were examined. The main target groups women, children, infants/toddlers. effects different types (wheat, maize, rice, soy, beans) status Results A random analysis before-after studies showed that led to significant increases mean haemoglobin level (3·360 g/l; 95 % CI: 0·980, 5·730) serum ferritin (4·518 µg/l; 2·367, 6·669); decreases anaemia (-6·7 %; -9·8 %, -3·6 %) deficiency (ID) (-10·4 -14·3 -6·5 %); but had no effect (IDA). controlled trials indicated (2·630 1·310, 3·950) (8·544 6·767, 10·320); (-8·1 -11·7 -4·4 %), ID (-12·0 -18·9 -5·1 IDA (-20·9 -38·4 -3·4 %). Conclusions Flour fortification with is an effective public health strategy improves populations worldwide.
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