A sensitive model of venous thrombosis in rats
作者： J. Hladovec
DOI: 10.1016/0049-3848(86)90073-3
关键词: Thrombus 、 Ketanserin 、 Dipyridamole 、 Anesthesia 、 Heparin 、 Thrombosis 、 Sulfinpyrazone 、 Venous thrombosis 、 Aspirin 、 Medicine 、 Hematology
摘要: Several antithrombotics (heparin, acetylsalicylic acid, sulfinpyrazone and dipyridamole) as well an antiserotonin ketanserin were tested in a new sensitive model of venous thrombosis rats. Intravenous injection hypotonic saline was used for thrombus induction combined with the vena cava ligation. Formation thrombi evaluated by their weights. With i.v. heparin, oral dipyridamole effective inhibition obtained, whereas remained incomplete.
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