Antiphospholipid Syndrome: A Challenging Hypercoagulable State with Systemic Manifestations

作者: Marco P. Donadini , Mark Crowther

DOI: 10.1016/J.HOC.2010.05.005

关键词: Systemic diseaseCardiologyCoagulopathyThrombosisVascular diseaseInternal medicineAutoimmune diseaseThrombophiliaPathologyImmunopathologyAntiphospholipid syndromeMedicine

摘要: Antiphospholipid syndrome (APS) is a systemic disease that causes venous and arterial thrombosis in virtually any organ responsible for fetal losses pregnancy disorders. Previously, APS was thought to be present mainly patients with lupus erythematosus. The spectrum of clinical manifestations wide, because the thrombotic process may involve vessels size organ. At present, there no evidence support or refute specific treatment strategies primary prophylaxis thrombosis.

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