Understanding variability in the BOLD signal and why it matters for aging
作者： Cheryl L. Grady , Douglas D. Garrett
DOI: 10.1007/S11682-013-9253-0
关键词: Cognition 、 Functional magnetic resonance imaging 、 Neuropsychology 、 Resting state fMRI 、 Noise (signal processing) 、 Signal 、 Neuroscience 、 Psychology 、 Bold fmri 、 Signal variability
摘要: Recent work in neuroscience supports the idea that variability brain function is necessary for optimal responsivity to a changing environment. In this review, we discuss series of functional magnetic resonance imaging (fMRI) studies younger and older adults assess age-related differences fMRI signal. This shows moment-to-moment signal represents an important “signal” within what typically considered measurement-related “noise” fMRI. accumulation evidence suggests moving beyond mean will provide complementary window into aging-related neural processes.
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