Characterization of a new type of human papillomavirus found in a lesion of Bowen's disease of the skin.

摘要: The genome of a human papillomavirus (HPV) found in patient with Bowen's disease the skin was molecularly cloned. Blot hybridization experiments, performed under stringent conditions, revealed no cross-hybridization between this HPV DNA and other known DNAs, showing that represents new type, tentatively named HPV34. In relaxed highest observed HPV16 DNA. physical map HPV34 aligned genetic by heteroduplex mapping. not detected 12 additional patients skin, but closely related one penile Bowenoid papulosis.