1-aminoalkyl-1h-indoles for treating glaucoma

作者: Jesse A. May , Hwang-Hsing Chen , Anura P. Dantanarayana

DOI:

关键词: Ocular hypertensionMedicineGlaucomaOphthalmology

摘要: 1-Aminoalkyl-1H-indoles receptor agonists (I) for treating ocular hypertension and glaucoma are disclosed.

参考文章(6)
Michael Bös, François Jenck, James R. Martin, Jean-Luc Moreau, Andrew J. Sleight, Jürgen Wichmann, Ulrich Widmer, Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder. Journal of Medicinal Chemistry. ,vol. 40, pp. 2762- 2769 ,(1997) , 10.1021/JM970030L
Richard John Hamlyn, Ashley Roger George, Jonathan Mark Bentley, David Reginald Adams, Suneel Gaur, Claire Elizabeth Dawson, Nathaniel Julius Monck, Jonathan Richard Anthony Roffey, Robert Mark Pratt, David Bebbington, Matthew Alexander James Duncton, Indoline derivatives as 5-ht2b and/or 5-ht2c receptor ligands ,(1999)
William Lee Seibel, Russell James Sheldon, Raymond Todd Henry, 2-imidazolinylaminoindole compounds useful as alpha-2 adrenoceptor agonists ,(1997)
Virendra Kumar, Edward Richard Bacon, Susan Jean Ward, Malcolm Rice Bell, Thomas Edward D'ambra, Philip Michael Carabateas, Michael Allen Eissenstat, John Peter Mallamo, 3-arylcarbonyl-1h-indoles useful as therapeutic agents ,(1991)
Milan Soukup, Mark Rogers-Evans, A process for the manufacture of 1-(amino-alkyl)-indoles ,(1997)