Colon selective drug delivery composition
作者： Chang-Baeg Lim , Chaul-Min Pai , Bo-Youn Seo , Sung-Bum La , Seoung-Seo Lee
DOI:
关键词: Materials science 、 Enzyme 、 Upper gastrointestinal 、 Gelatin 、 Drug delivery 、 Biochemistry 、 Polysaccharide
摘要: A composition comprising gelatin and a polysaccharide which is degradable by colonic enzyme and, optionally, with an aldehyde and/or polyvalent metal ion additional polysaccharide, not degraded or disintegrated in the upper gastrointestinal tract, thereby rendering active substance loaded therein to be selectively delivered colon effectively released colon.
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