Method for selectively binding a substrate to sorbents by way of at least bivalent bonds

作者: Klaus Gottschall

DOI:

关键词: SorbentCombinatorial chemistryChemistryBivalent (genetics)

摘要: The invention relates to a method for selectively binding at least one sorbent substrate having two different groups capable of binding. inventive is characterized by comprising steps (i) (iv): determining from synthetic or natural first substrate, (ii) applying that are second carrier each, thereby forming sorbent, whereby the same step complementary non-complementary thereto, and according (i), (iii) contacting may be with (ii), (iv) testing strength (iii), while using whose production comprises (ii). also combinatorial library which collection sorbents each.

参考文章(10)
Christopher J. Welch, Bhat Ganapati, Marina Protopopova, Method for screening chromatographic adsorbents ,(1999)
Igor A. Luzinov, Bogdan V. Zdyrko, Viktor Z. Klep, Killugudi L. Swaminatha Iyer, Surface modification of substrates ,(2004)
Heidi Händel, Elke Gesele, Klaus Gottschall, Klaus Albert, Application of HRMAS 1H NMR Spectroscopy To Investigate Interactions between Ligands and Synthetic Receptors Angewandte Chemie International Edition. ,vol. 42, pp. 438- 442 ,(2003) , 10.1002/ANIE.200390133
Noubar B Afeyan, Laszlo Varady, Fred E Regnier, None, Molecular imaging method ,(1993)