Murburn concept: A facile explanation for oxygen-centered cellular respiration
作者： Kelath Murali Manoj
DOI:
关键词: Inner mitochondrial membrane 、 Biology 、 Cellular respiration 、 ATP synthase 、 Mitochondrion 、 Oxygen 、 Flavin group 、 Nanotechnology 、 Cellular metabolic process 、 Biophysics 、 Oxidative phosphorylation
摘要: Via a concomitant communication (the first part of my work), I have conclusively debunked the prevailing explanations for mitochondrial oxidative phosphorylation and established need novel rationale to account reaction paradigm. Towards same, murburn concept is hereby floated as viable explanation (in second work). It proposed that inner membrane (harboring various metal flavin enzyme complexes) serves means confine stabilize radical reactions, which effectively couple bring about ATP synthesis in proton-deficient microcosm. The scheme un-ordered favored by Ockham's razor evolutionary perspectives. Murburn paradigm-shift biochemistry because it advocates diffusible reactive (oxygen) species are mainstay routine cellular metabolic process within mitochondria.
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