The prevalence and impact of alcohol problems in major depression: a systematic review.

摘要: Major depression and alcohol problems are common in primary care, yet little is known about the prevalence of patients with or alcohol's effect on outcomes. We strove to answer following questions: How depression? Does affect course depression, response antidepressant therapy, risk suicide/death, social functioning health care utilization? In which categories treatment settings have been evaluated? English language studies from MEDLINE, PsychINFO, Cochrane Controlled Trial Registry were reviewed. Studies selected using predefined criteria if they reported effects depression. Thirty-five met revealed a median current lifetime 16% (range 5-67%) 30% 10-60%), respectively. This compares 7% for 16-24% general population. There evidence that antidepressants improve outcomes persons dependence. Alcohol associated worse respect course, suicide/death risk, functioning, utilization. The majority studies, 34 35 (97%), evaluated abuse dependence, 25 (71%) conducted psychiatric inpatients. conclude more than population, adverse clinical utilization outcomes, can be effective presence addition, literature focuses almost exclusively dependence inpatient settings, excludes less severe outpatient settings.