Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial

作者: Charles S Fuchs , Jiri Tomasek , Cho Jae Yong , Filip Dumitru , Rodolfo Passalacqua

DOI: 10.1016/S0140-6736(13)61719-5

关键词: Clinical trialInternal medicineHazard ratioClinical endpointAdverse effectSurgeryPlaceboGastroenterologyMedicineIntention-to-treat analysisRandomized controlled trialRamucirumab

摘要: … We aimed to assess whether ramucirumab, a monoclonal antibody VEGFR-2 antagonist, … , to receive best supportive care plus either ramucirumab 8 mg/kg or placebo, intravenously …

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