PSYCHOLOGICAL STRESS AND VASCULAR DISTURBANCES IN ROSACEA

摘要: Rosacea is a chronic skin disorder, characterized by redness and flushing of the cheeks, nose, chin or forehead. It has been proposed that rosacea result frequent blushing (Miller, 1921; Klaber & Whittkower, 1939). However, relationship between uncertain. The aim present research was to investigate psychological stress vascular disturbances in rosacea. Five studies were conducted. first study explored mental health while next two investigated responses sufferers controls acetylcholine (which induces endothelial vasodilatation axon reflexes) (embarrassment). fourth aimed examine indicators symptoms on daily basis. fifth consisted three case looking at use Cognitive Behavioural Therapy (CBT) Task Concentration Training (TCT) with presenting social anxiety fear symptoms. In 1, sixty-two participants asked complete Blushing Propensity Scale (BPS), Fear Negative Evaluation (FNE), Depression, Anxiety Stress (DASS), Social Interaction (SIAS) Phobia (SPS). Outcomes from indicated Type 2 (n= 12) perceived themselves as more frequently intensely than 1 (n=19) (n=31). This suggested experiencing may have lower sensitivity threshold episodes. In addition, stressed controls, possibly indicating managing condition can be stressful. Contrary previous reports (Gupta et al., 2006; National Society, 2005) severity not associated depression, negative evaluation. few who reported high scores offered intervention (Study 5). The second sufferers. Cutaneous reflex function assessed using an dose response curve. inducing flare ACh iontophoresis. this had greater Thus over-reactivity might contribute prolonged vasodilatation. cutaneous similar control groups. results neural pathways mediated rather function. third facial blood flow attempted laboratory induced embarrassment tasks. found region during singing speech tasks, suggesting blushed type controls. Furthermore, higher ratings emotionally aroused other participants. Taken together, it would appear combination physiological cognitive factors increased tasks. Using diary, 15 recorded their stress, mood intensity daily. stinging/facial same day for months. stinging day. feeling anxious having low related increase presence where occurred should taken into consideration when formulating interventions sufferers. 5, individual provided helpful Encouragingly, all gain repertoire strategies showed decrease assessment questionnaires following intervention. Replication protocol investigation approaches are required establish best practise outcome require interventions. findings suggest reflexes contributes flushing. emotional appears maintained factors. On clinical level, recommends targeted