Coronary aneurysms in infants and young children with acute febrile mucocutaneous lymph node syndrome

摘要: In 1967, Kawasaki, in Japan, first described a new syndrome affecting infants and young children—an acute, febrile illness with mucocutaneous involvement associated swelling of cervical lymph nodes. The prognosis is usually good but recently it has become evident that 1–2% the patients die suddenly from acute heart failure. Infantile polyarteritis (nodosa-like arteritis) accompanied by coronary aneurysm thrombosis been noted postmortem examinations. Twenty surviving were examined angiography; 12 20 had abnormal angiograms; seven aneurysms. Complete regression aneurysms was proved two at subsequent angiography. One patient developed mitral regurgitation as result papillary muscle dysfunction. without symptoms years after onset illness.