The Metabolism and Functions of [gamma]-Aminobutyric Acid.
作者： A. W. Bown , B. J. Shelp
DOI: 10.1104/PP.115.1.1
关键词: Stereochemistry 、 Enzyme 、 Carbon-Carbon Lyases 、 Citric acid cycle 、 Biology 、 Metabolism 、 gamma-Aminobutyric acid 、 Carboxy-lyases 、 Biochemistry 、 Glutamate decarboxylase
摘要: GABA is a four-C, nonprotein amino acid found in virtually all prokaryotic and eukaryotic organisms as a significant component of the free amino acid pool. In higher plants GABA is synthesized primarily through the H+-consuming a-decarboxylation of L-glutamate (L-Glu) in a reaction (L-Glu+ H+-+ GABA+ CO,) catalyzed by LG~ u decarboxylase (EC 4.1. 1.15). It is metabolized through a reversible transamination (GABA+ pyruvate= succinic semialdehyde+ Ala) catalyzed by GABA transaminase (EC 2.6. 1.19). The product of …
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