Cisplatin resistance in human cancers.
作者： K.J. Scanlon , M. Kashani-Sabet , T. Tone , T. Funato
DOI: 10.1016/0163-7258(91)90033-I
关键词: Cancer 、 Gene 、 Immunology 、 Gene expression 、 Cytotoxicity 、 Drug resistance 、 Cisplatin 、 Biology 、 Cell culture 、 Cancer research 、 Regulation of gene expression
摘要: Cancer chemotherapeutic agents primarily act by damaging cellular DNA directly or indirectly. Tumor cells, in contrast to normal respond cisplatin with transient gene expression protect and/or repair their chromosomes. Repeated treatments results a stable resistant cell line enhanced but lacking amplification for the proteins that will limit cytotoxicity. Recently, several new human lines have been characterized resistance. These led better understanding of molecular and biochemical basis The c-fos proto-oncogene, master switch turning on other genes response wide range stimuli, has shown play an important role resistance both vitro patients. Based these studies, strategies developed circumvent exploit clinical
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sci-hub.se 参考文章(266)
Motoko SHIBANUMA, Toshio KUROKI, Kiyoshi NOSE, Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport. FEBS Journal. ,vol. 164, pp. 15- 19 ,(1987) , 10.1111/J.1432-1033.1987.TB10985.X
P Mistry, LR Kelland, G Abel, S Sidhar, KR Harrap, The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines British Journal of Cancer. ,vol. 64, pp. 215- 220 ,(1991) , 10.1038/BJC.1991.279
H. Erlich, D. Gelfand, J. Sninsky, Recent advances in the polymerase chain reaction Science. ,vol. 252, pp. 1643- 1651 ,(1991) , 10.1126/SCIENCE.2047872
Kathy S. Albain, Lode J. Swinnen, Leonard C. Erickson, Patrick J. Stiff, Richard I. Fischer, Cisplatin preceded by concurrent cytarabine and hydroxyurea: a pilot study based on an in vitro model. Cancer Chemotherapy and Pharmacology. ,vol. 27, pp. 33- 40 ,(1990) , 10.1007/BF00689273
MC Etienne, S Bernard, JL Fischel, P Formento, J Gioanni, J Santini, F Demard, M Schneider, G Milano, Dose reduction without loss of efficacy for 5-fluorouracil and cisplatin combined with folinic acid. In vitro study on human head and neck carcinoma cell lines. British Journal of Cancer. ,vol. 63, pp. 372- 377 ,(1991) , 10.1038/BJC.1991.88
Edward M. Newman, Ying Lu, Mohammed Kashani-Sabet, Vellapan Kesavan, Kevin J. Scanlon, Mechanisms of cross-resistance to methotrexate and 5-fluorouracil in an A2780 human ovarian carcinoma cell subline resistant to cisplatin Biochemical Pharmacology. ,vol. 37, pp. 443- 447 ,(1988) , 10.1016/0006-2952(88)90212-2
D. A. Engel, U. Muller, R. W. Gedrich, J. S. Eubanks, T. Shenk, Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 3957- 3961 ,(1991) , 10.1073/PNAS.88.9.3957
Margaret Fox, John J. Roberts, Drug resistance and DNA repair. Cancer and Metastasis Reviews. ,vol. 6, pp. 261- 281 ,(1987) , 10.1007/BF00144267
Harunobu Amagase, Masanori Kakimoto, Ken Hashimoto, Tohru Fuwa, Shigeru Tsukagoshi, Epidermal growth factor receptor-mediated selective cytotoxicity of antitumor agents toward human xenografts and murine syngeneic solid tumors. Japanese Journal of Cancer Research. ,vol. 80, pp. 670- 678 ,(1989) , 10.1111/J.1349-7006.1989.TB01695.X
Robert E. Kingston, Bernd-Uwe Sevin, Reinaldo Ramos, Manno Saks, Daniel Donato, Maureen A. Jarrell, Hervy E. Averette, Synergistic effects of cis-platinum (CP) and cytosine arabinoside (ara-C) on ovarian carcinoma cell lines demonstrated by dual-parameter flow cytometry (FCM) Gynecologic Oncology. ,vol. 32, pp. 282- 287 ,(1987) , 10.1016/0090-8258(89)90625-2