Antithrombotic Therapy After Peripheral Vascular Intervention

作者: Peter Hu , Schuyler Jones

DOI: 10.1007/S11886-016-0706-0

关键词: Emergency medicineClopidogrelObservational studyDiseaseSurgeryMedicineP2Y12Critical limb ischemiaRandomized controlled trialAntithromboticAspirinCardiology and Cardiovascular Medicine

摘要: Cardioprotective medications and risk-factor modification are the hallmarks of treatment for all patients with peripheral artery disease (PAD). If symptoms life-limiting and/or do not respond to conservative treatment, endovascular or surgical revascularization can be considered especially critical limb ischemia acute ischemia. The rates vascular intervention (PVI) have risen dramatically over past few decades much this care shifted from inpatient hospital settings outpatient office-based clinics. While PVI surged technology advancements changed face PVI, data behind optimal antithrombotic therapy following is scant. Currently in USA, most treated indefinite aspirin a variable duration clopidogrel (or other P2Y12 inhibitor)-typically 1 month, 3 months, therapy. More observational analyses randomized clinical trials evaluating clinically relevant outcomes such as cardiovascular morbidity/mortality risk bleeding needed guide role post-PVI.

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