作者: Peter Hu , Schuyler Jones
DOI: 10.1007/S11886-016-0706-0
关键词: Emergency medicine 、 Clopidogrel 、 Observational study 、 Disease 、 Surgery 、 Medicine 、 P2Y12 、 Critical limb ischemia 、 Randomized controlled trial 、 Antithrombotic 、 Aspirin 、 Cardiology and Cardiovascular Medicine
摘要: Cardioprotective medications and risk-factor modification are the hallmarks of treatment for all patients with peripheral artery disease (PAD). If symptoms life-limiting and/or do not respond to conservative treatment, endovascular or surgical revascularization can be considered especially critical limb ischemia acute ischemia. The rates vascular intervention (PVI) have risen dramatically over past few decades much this care shifted from inpatient hospital settings outpatient office-based clinics. While PVI surged technology advancements changed face PVI, data behind optimal antithrombotic therapy following is scant. Currently in USA, most treated indefinite aspirin a variable duration clopidogrel (or other P2Y12 inhibitor)-typically 1 month, 3 months, therapy. More observational analyses randomized clinical trials evaluating clinically relevant outcomes such as cardiovascular morbidity/mortality risk bleeding needed guide role post-PVI.