INTRODUCTION OF CENTER OF CHIRALITY INTO FLUOROCOMPOUNDS BY MICROBIAL TRANSFORMATION OF 2,2,2-TRIFLUOROETHANOL

作者: Tomoya Kitazume , Nobuo Ishikawa

DOI: 10.1246/CL.1984.1815

关键词: Chirality (chemistry)Organic chemistryChemistryMicrobial transformationBiotransformationStereochemistryBond formation2,2,2-TrifluoroethanolYeastEnantioselective synthesis

摘要: 2,2,2-Trifluoroethanol is found to be a valuable synthetic tool proceeding the chiral trifluoromethylated compounds via enantiotopic differentiating reaction and carbon-carbon bond formation with active fermenting baker’s yeast.

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