Análise da resposta hormonal pancreática antes e após tratamento com GLP-1 mimético em indivíduos com diabetes tipo 2 portadores da variante rs7903146 do gene TCF7L2

作者: Mari Cassol Ferreira

DOI: 10.11606/T.5.2013.TDE-01112013-113904

关键词: Medicine

摘要:

参考文章(78)
David Altshuler, Joel N. Hirschhorn, Mia Klannemark, Cecilia M. Lindgren, Marie-Claude Vohl, James Nemesh, Charles R. Lane, Stephen F. Schaffner, Stacey Bolk, Carl Brewer, Tiinamaija Tuomi, Daniel Gaudet, Thomas J. Hudson, Mark Daly, Leif Groop, Eric S. Lander, The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genetics. ,vol. 26, pp. 76- 80 ,(2000) , 10.1038/79216
Valeriya Lyssenko, Roberto Lupi, Piero Marchetti, Silvia Del Guerra, Marju Orho-Melander, Peter Almgren, Marketa Sjögren, Charlotte Ling, Karl-Fredrik Eriksson, Rita Mancarella, Göran Berglund, Tiinamaija Tuomi, Peter Nilsson, Stefano Del Prato, Leif Groop, None, Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes Journal of Clinical Investigation. ,vol. 117, pp. 2155- 2163 ,(2007) , 10.1172/JCI30706
Younes Anini, Patricia L. Brubaker, Muscarinic receptors control glucagon-like peptide 1 secretion by human endocrine L cells. Endocrinology. ,vol. 144, pp. 3244- 3250 ,(2003) , 10.1210/EN.2003-0143
Randall T. Moon, Aimee D. Kohn, Giancarlo V. De Ferrari, Ajamete Kaykas, WNT and β-catenin signalling: diseases and therapies Nature Reviews Genetics. ,vol. 5, pp. 691- 701 ,(2004) , 10.1038/NRG1427
Nitika Arora Gupta, Jamie Mells, Richard M. Dunham, Arash Grakoui, Jeffrey Handy, Neeraj Kumar Saxena, Frank A. Anania, Glucagon‐like peptide‐1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway Hepatology. ,vol. 51, pp. 1584- 1592 ,(2010) , 10.1002/HEP.23569
M. Horikoshi, K. Hara, C. Ito, R. Nagai, P. Froguel, T. Kadowaki, A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia. ,vol. 50, pp. 747- 751 ,(2007) , 10.1007/S00125-006-0588-6
M. A. Nauck, I. Vardarli, C. F. Deacon, J. J. Holst, J. J. Meier, Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? Diabetologia. ,vol. 54, pp. 10- 18 ,(2011) , 10.1007/S00125-010-1896-4
James Malone, Michael Trautmann, Ken Wilhelm, Kristin Taylor, David M Kendall, Exenatide once weekly for the treatment of type 2 diabetes. Expert Opinion on Investigational Drugs. ,vol. 18, pp. 359- 367 ,(2009) , 10.1517/13543780902766802
M COMBETTES, GLP-1 and type 2 diabetes: physiology and new clinical advances. Current Opinion in Pharmacology. ,vol. 6, pp. 598- 605 ,(2006) , 10.1016/J.COPH.2006.08.003