BMI-1 silencing significantly reduces gene expression of DNA damage repair markers in human breast cancer (1047.5)
作者： Alfredo Ribeiro-Silva , João Paulo Oliveira-Costa , Giórgia Silveira , Danilo Soave , Mara Celes
DOI: 10.1096/FASEBJ.28.1_SUPPLEMENT.1047.5
关键词: Locus (genetics) 、 Gene silencing 、 Cancer research 、 DNA 、 DNA Damage Repair 、 Cell immortalization 、 Human breast 、 Biology 、 Gene expression 、 Homologous recombination
摘要: Homologous recombination has a major role in DNA double-strand break repair. BMI-1 been associated with cell immortalization through the supression of INK4a/ARF locus, thereby allowing that DNA...
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