Graphene for Glucose, Dopamine, Ascorbic Acid, and Uric Acid Detection

作者: Yuwei Hu , Fenghua Li , Dongxue Han , Li Niu

DOI: 10.1007/978-3-662-45695-8_4

关键词: CatalysisBiosensorElectron transport chainEnzyme catalysisCombinatorial chemistryBiomoleculeGrapheneAscorbic acidUric acidChemistry

摘要: Since every atom in graphene single sheet is a surface atom, molecular interaction and electron transport through can be highly sensitive to adsorbed biomolecules. Graphene materials act as good candidates for glucose sensing due the high area, excellent conductivity, small band gap, which are favorable biomolecules loading electrons conducting. Generally, graphene-based platforms determination could categorized into two kinds, namely enzyme catalysis non-enzyme catalysis. The shows sensitivity selectivity. However, inevitable drawbacks of instability originating from intrinsic nature enzyme, well critical operational conditions complicated immobilization procedure, may limit analytical applications. These overcome catalytic biosensors, stable, simple, reliable, cost-effective. Detailed descriptions illustrated following. concentrations dopamine (DA), ascorbic acid (AA), uric (UA) human body important diagnosis, monitoring, prevention, treatments some certain diseases, such HIV infections, schizophrenia, Parkinson, hyperuricemia, type arthritis. Then various detection quantification DA, AA, UA also demonstrated.

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