Gut Microbiome, Intestinal Permeability, and Tissue Bacteria in Metabolic Disease: Perpetrators or Bystanders?

作者: Rima M. Chakaroun , Lucas Massier , Peter Kovacs

DOI: 10.3390/NU12041082

关键词: BioinformaticsSystemic inflammationMetabolic diseaseBiologyGut permeabilityBacteriaIntestinal permeabilityGut microbiomeGut floraClinical evidence

摘要: … gut microbiota shifts, increased intestinal permeability in metabolic disease, and the critical positioning of the intestinal barrier … , it is essential that the intestinal immune system is tolerant …

参考文章(222)
Shanthi Sitaraman, Xia Liu, Laetitia Charrier, Li Hao Gu, Thomas R. Ziegler, Andrew Gewirtz, Didier Merlin, Colonic leptin: source of a novel proinflammatory cytokine involved in IBD The FASEB Journal. ,vol. 18, pp. 696- 698 ,(2004) , 10.1096/FJ.03-0422FJE
Rémy Burcelin, Matteo Serino, Chantal Chabo, Lucile Garidou, Celine Pomié, Michael Courtney, Jacques Amar, Anne Bouloumié, Metagenome and metabolism: the tissue microbiota hypothesis. Diabetes, Obesity and Metabolism. ,vol. 15, pp. 61- 70 ,(2013) , 10.1111/DOM.12157
Jeffrey M. Friedman, Jeffrey L. Halaas, Leptin and the regulation of body weight in mammals Nature. ,vol. 395, pp. 763- 770 ,(1998) , 10.1038/27376
Iurii Koboziev, Fridrik Karlsson, Matthew B. Grisham, Gut‐associated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation Annals of the New York Academy of Sciences. ,vol. 1207, pp. 86- ,(2010) , 10.1111/J.1749-6632.2010.05711.X
Lise Pedersen, Mads Nybo, Mikael Kjær Poulsen, Jan Erik Henriksen, Jordi Dahl, Lars Melholt Rasmussen, Plasma calprotectin and its association with cardiovascular disease manifestations, obesity and the metabolic syndrome in type 2 diabetes mellitus patients BMC Cardiovascular Disorders. ,vol. 14, pp. 196- 196 ,(2014) , 10.1186/1471-2261-14-196
Peter J. Turnbaugh, Jeffrey I. Gordon, The core gut microbiome, energy balance and obesity The Journal of Physiology. ,vol. 587, pp. 4153- 4158 ,(2009) , 10.1113/JPHYSIOL.2009.174136
Karin de Punder, Leo Pruimboom, Stress Induces Endotoxemia and Low-Grade Inflammation by Increasing Barrier Permeability Frontiers in Immunology. ,vol. 6, pp. 223- 223 ,(2015) , 10.3389/FIMMU.2015.00223
Aleksandra Duda-Chodak, Tomasz Tarko, Paweł Satora, Paweł Sroka, Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review European Journal of Nutrition. ,vol. 54, pp. 325- 341 ,(2015) , 10.1007/S00394-015-0852-Y