Epitope mapping of antibodies towards human protein targets

作者: Barbara Hjelm

DOI:

关键词: Computational biologyInteraction siteBiologyEpitope mappingAntigenImmunologyAntibody

摘要: This thesis, based on five research papers, presents results from development and evaluation ofmethods for identifying the interaction site of antibodies their antigens functional invest ...

参考文章(149)
Emil Fischer, Über die Hydrolyse der Proteïnstoffe Springer, Berlin, Heidelberg. pp. 621- 623 ,(1906) , 10.1007/978-3-642-99499-9_43
John Löfblom, Mathias Uhlén, Johan Rockberg, Björn Forsström, Barbara Hjelm, Immunizations of inbred rabbits using the same antigen yield antibodies with similar, but not identical, epitopes ,(2012)
Frank W. Putnam, Mitsuo Kozuru, Caroline W. Easley, Structural Studies of the Immunoglobulins Journal of Biological Chemistry. ,vol. 242, pp. 2435- 2446 ,(1967) , 10.1016/S0021-9258(18)95980-6
C.A. Hutchison, S. Phillips, M.H. Edgell, S. Gillam, P. Jahnke, M. Smith, Mutagenesis at a specific position in a DNA sequence. Journal of Biological Chemistry. ,vol. 253, pp. 6551- 6560 ,(1978) , 10.1016/S0021-9258(19)46967-6
182. Colwill K, Renewable Protein Binder Working Group, Dübel S In vitro Antibody Consortium, Persson H, Jarvik NE, Wyrzucki A, Wojcik J, Koide A, Kossiakoff AA, Koide S, Sidhu S, Dyson MR, Pershad K, Pavlovic JD, Karatt-Vellatt A, Schofield DJ, Kay BK, McCafferty J, Mersmann M, Meier D, Mersmann J, Helmsing S, Hust M, Nice E Monash Antibody Technologies Facility, Berkowicz S, Freemantle A, Spiegel M, Sawyer A, Layton D, Pawson T Pawson Laboratory, Dai A, Rocks O, Williton K, Fellouse FA, Hersi K, Uhlén M Human Protein Atlas, Nilsson P, Sundberg M, Sjöberg R, Sivertsson A, Schwenk JM, Takanen JO, Hober S, Gräslund S Structural Genomics Consortium, Dahlgren LG, Flores A, Johansson I, Weigelt J, Crombet L, Loppnau P, Kozieradzki I, Cossar D, Arrowsmith CH, Edwards AM, A roadmap to generate renewable protein binders to the human proteome Nature Methods. ,vol. 8, pp. 551- 558 ,(2011) , 10.1038/NMETH.1607
Hubert Bradford Vickery, The origin of the word protein. Yale Journal of Biology and Medicine. ,vol. 22, pp. 387- 393 ,(1950)
R R Porter, The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain Biochemical Journal. ,vol. 73, pp. 119- 127 ,(1959) , 10.1042/BJ0730119
Peter Nilsson, Linda Paavilainen, Karin Larsson, Jenny Ödling, Mårten Sundberg, Ann-Catrin Andersson, Caroline Kampf, Anja Persson, Cristina Al-Khalili Szigyarto, Jenny Ottosson, Erik Björling, Sophia Hober, Henrik Wernérus, Kenneth Wester, Fredrik Pontén, Mathias Uhlen, Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling. Proteomics. ,vol. 5, pp. 4327- 4337 ,(2005) , 10.1002/PMIC.200500072
M.H.V. Van Regenmortel, G.Daney de Marcillac, An assessment of prediction methods for locating continuous epitopes in proteins. Immunology Letters. ,vol. 17, pp. 95- 107 ,(1988) , 10.1016/0165-2478(88)90076-4