Lung Cancer and Exposure to Tobacco Smoke in the Household

摘要: BACKGROUND The relation between passive smoking and lung cancer is of great public health importance. Some previous studies have suggested that exposure to environmental tobacco smoke in the household can cause cancer, but others found no effect. Smoking by spouse has been most commonly used measure this exposure. METHODS In order determine whether associated with within household, we conducted a population-based case--control study 191 patients histologically confirmed primary who had never smoked an equal number persons without smoked. Lifetime residential histories including information on were compiled analyzed. Exposure was measured terms "smoker-years," determined multiplying years each residence smokers household. RESULTS Household 25 or more smoker-years during childhood adolescence doubled risk (odds ratio, 2.07; 95 percent confidence interval, 1.16 3.68). Approximately 15 control subjects reported level less than did not increase cancer. spouse's smoking, which constituted one third total average, risk. CONCLUSIONS possibility recall bias other methodologic problems may influence results case-control smoke. Nonetheless, our findings regarding early life suggest approximately 17 cancers among nonsmokers be attributed high levels cigarette adolescence.