Diagnostic methods of multiple organ amyloidosis
作者： Francine Gervais
DOI:
关键词: Diagnostic methods 、 Amyloidosis 、 Allele 、 Antibody 、 Hepatocyte growth factor 、 Immunoglobulin light chain 、 Serum amyloid A 、 Serum albumin 、 Pathology 、 Biology
摘要: Described are methods of assessing whether a subject has or is at risk having multiple organ amyloidosis (MOA) The method includes detecting diagnostically predictive collection biomarkers amyloidosis, wherein the detection indicates Also described monitoring treatment subjects with and evaluating therapeutic compounds Representative for use in may be selected from variant serum amyloid A (SAA) allele, elevated SAA level, C-reactive protein (CRP) depressed glycosammoglycan (GAG) mterleukm -18 (IL-18) macrophage-colony stimulating factor (M-CSF) hepatocyte growth (HGF) presence an antibody against citrullmated vimentm (Sa), monoclonal immunoglobulin light chain, increased albumin, creatinine clearance
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