Method for producing an intermediate product of dabigatran etexilate
作者： Georg Zerban , Arndt Hausherr , Rainer Hamm , Christian Filser , Gunter Koch
DOI:
关键词: Combinatorial chemistry 、 Intermediate product 、 Diamine 、 Chemistry 、 Ammonia 、 Sulfonic acid 、 Amidine
摘要: The invention relates to a method for producing the compound of formula 1, characterized in that diamine 2 is converted 4 by reaction with an oxadiazolone 3, said being amidine 1 without isolation hydrating and adding p-toluene sulfonic acid ammonia.
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