Hyperglycemia in severe traumatic brain injury patients and its association with thirty-day mortality: a prospective observational cohort study in Uganda

摘要: Background Traumatic brain injury (TBI) is a growing public health concern that can be complicated with an acute stress response. This response may assessed by monitoring blood glucose levels but this not routine in remote settings. There paucity of data on the prevalence hyperglycemia and variables associated mortality after severe TBI Uganda. Objective We aimed to determine patients 30-day at Mulago National Referral Hospital Methods consecutively enrolled cohort 99 TBI. Serum were measured admission 24 h. Other study included: mechanism injury, CT findings, location size hematoma, socio-demographics. The main outcome was 30 days management compared more than 11.1 mmol/L those without. Results Most (92.9%) male aged 18-30 years (47%). Road Traffic Collisions most common cause (64.7%) followed assault (17.1%) falls (8.1%). Nearly one six admitted mmol/L. rate 68.8% (OR 1.47; 95% CI [0.236-9.153]; P = 0.063) against 43.7% without hyperglycemia. presence hypothermia 10.17; [1.574-65.669]; 0.015) convulsions 5.64; [1.541-19.554]; 0.009) significant predictors mortality. Conclusion Hypothermia major Early following appears occur tendency towards high These findings justify could form basis for establishing sugar control protocol such