Role of Antiplatelet Therapies in Preventing Atherothrombosis

摘要: Platelets exhibit a major role in development and progression of atherothrombosis. The normal function platelets is to secure hemostasis at sites vascular injuries. Abnormal endovascular structure may result excessive platelet with consequence progressive or acute reduction lumen cessation blood flow. Despite succeeding averting bleeding, total occlusion vessel leads inevitable ischemia eventual cell death upon lack supply clinically manifesting as myocardial infarction coronary vessels, cerebral (stroke) peripheral gangrene arterial disease. Antiplatelets long have been used halt the process atherothrombosis preventing further tissue damage expense bleeding well other side effects. In this review, antiplatelets primary secondary prevention thrombotic events explored light evidence based clinical practice.