Tailoring lipid nanoconstructs for the oral delivery of paliperidone: Formulation, optimization and in vitro evaluation

作者: Saleha Rehman , Bushra Nabi , Sanjula Baboota , Javed Ali

DOI: 10.1016/J.CHEMPHYSLIP.2020.105005

关键词: PaliperidoneChemistrySolubilizationBox–Behnken designBiopharmaceuticalChromatographySonicationQuality by DesignPermeationIn vitro

摘要: Purpose The present research work involves Quality by Design (QbD)-based fabrication of lipid nanoconstructs (LNC) of paliperidone (PPD) bearing superior biopharmaceutical …

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