Neurobiology of rodent self-grooming and its value for translational neuroscience

作者: Allan V. Kalueff , Adam Michael Stewart , Cai Song , Kent C. Berridge , Ann M. Graybiel

DOI: 10.1038/NRN.2015.8

关键词: Autism spectrum disorderNeuroscienceTranslational neurosciencePsychologyExtramuralRodentBiological neural networkSelf groomingObsessive compulsiveValue (mathematics)General Neuroscience

摘要: Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing pattern and one of the most frequently performed behavioural activities in rodents. In this Review, we discuss neurobiology rodent self-grooming, highlight studies models neuropsychiatric disorders--including autism spectrum disorder obsessive compulsive disorder--that have assessed self-grooming phenotypes. We suggest that may be useful measure repetitive such models, therefore value to translational psychiatry. Assessment also for understanding neural circuits are involved sequential patterns action.

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