Circulating tumor cells (Ctc) and kras mutant circulating free Dna (cfdna) detection in peripheral blood as biomarkers in patients diagnosed with exocrine pancreatic cancer.

作者: Julie Earl , Sandra Garcia-Nieto , Jose Carlos Martinez-Avila , José Montans , Alfonso Sanjuanbenito

DOI: 10.1186/S12885-015-1779-7

关键词: Stem cellPancreatic cancerPathologyExocrine pancreatic cancerInternal medicineOncologySurgical oncologyCirculating tumor cellDiseaseMedicineSurvival rateKRAS

摘要: Background Pancreatic cancer remains one of the most difficult cancers to treat with poorest prognosis. The key improving survival rates in this disease is early detection and monitoring disseminated residual disease. However, hindered due lack reliable diagnostic predictive markers which mean that majority patients succumb their condition within a few months.

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