Genomics Approach to Bioremediation

摘要: A range of pollutants are being added to the environment by human activities. Majority these contaminants chemically synthesized compounds also termed as xenobiotics. Some persist in for longer periods due presence structural elements or constituents that do not occur naturally nature and therefore resistant attack degradative enzymes. Pollutants like nitro aromatics, polycyclic aromatics biphenyls degraded relatively within a short period time transformed into non-toxic end products owing microbial degradation. However, highly nitrated halogenated well pesticides explosives inert with half-lives under native conditions making them recalcitrant. Due their poor water solubility they tend enter food web subsequently biomagnified. In addition, many often metabolized mammalian cells resulting intermediates potentially mutagenic carcinogenic agents (Henschler et al., 2001; Galloway Handy, 2003). This has led imposition prohibition on use several compounds. Apart from this, large quantity radioactive waste is generated byproduct nuclear plants generating atomic energy. bio-hazardous disposed multiple dumping sites worldwide. Currently there no efficient technology store this safely. Radio nuclides need be detoxified effectively immobilized prevent leaking contaminated sites. Ecological disasters accidental spills accumulated toxic waste, only affects terrestrial ecosystem marine life but influences economy area (Samanta 2002; Brim 2003; Regueiro 2007).